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CG2875 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31326, updated on 4-Jan-2025

Summary

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Official Symbol
CG2875provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0029672
Locus tag
Dmel_CG2875
See related
AllianceGenome:FB:FBgn0029672
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG2875
Summary
Predicted to be involved in ribosome biogenesis. Predicted to be part of Noc4p-Nop14p complex and small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval midgut primordium; larval visceral muscle cell; and trunk visceral muscle primordium. Orthologous to human NOC4L (nucleolar complex associated 4 homolog). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG2875 in Genome Data Viewer
Location:
3D6-3D6; 1-3 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (3571456..3573622, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (3465489..3467655, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44999 Neighboring gene Dpr-interacting protein alpha Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR34335 Neighboring gene pickpocket 8 Neighboring gene Allatostatin A receptor 1 Neighboring gene Insulin-like peptide 7 Neighboring gene Poly(ADP-ribose) glycohydrolase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A transcriptional network controlling glial development in the Drosophila visual system. Bauke AC, et al. Development, 2015 Jun 15. PMID 26015542
  2. Drosophila nucleostemin 3 is required to maintain larval neuroblast proliferation. Johnson PW, et al. Dev Biol, 2018 Aug 1. PMID 29679561, Free PMC Article
  3. WAC Regulates mTOR Activity by Acting as an Adaptor for the TTT and Pontin/Reptin Complexes. David-Morrison G, et al. Dev Cell, 2016 Jan 25. PMID 26812014, Free PMC Article
  4. Basic leucine zipper protein Cnc-C is a substrate and transcriptional regulator of the Drosophila 26S proteasome. Grimberg KB, et al. Mol Cell Biol, 2011 Feb. PMID 21149573, Free PMC Article
  5. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins. Edlich-Muth C, et al. J Mol Biol, 2015 May 22. PMID 25813344, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Noc4p-Nop14p complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG2875-PA
CG2875-PB
CG2875-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    3571456..3573622 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272290.1 → NP_001259219.1  uncharacterized protein Dmel_CG2875, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259219.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W4R2
    Conserved Domains (1) summary
    pfam03914
    Location:286 → 434
    CBF; CBF/Mak21 family

  2. NM_166981.2 → NP_726876.1  uncharacterized protein Dmel_CG2875, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_726876.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W4R2
    Related
    FBpp0070562
    Conserved Domains (1) summary
    pfam03914
    Location:286 → 434
    CBF; CBF/Mak21 family

  3. NM_130713.3 → NP_570069.1  uncharacterized protein Dmel_CG2875, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_570069.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W4R1
    Related
    FBpp0070561
    Conserved Domains (1) summary
    pfam03914
    Location:287 → 435
    CBF; CBF/Mak21 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W4R1 Q9W4R1
Q9W4R2 Q9W4R2

Gene LinkOut

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