Fas2 - Fasciclin 2

Predicted to enable cell-cell adhesion mediator activity. Involved in several processes, including neuron development; regulation of tube size, open tracheal system; and synapse organization. Located in several cellular components, including distal axon; muscle cell postsynaptic specialization; and synaptic membrane. Is expressed in several structures, including larval neurons; neurohemal organ; neuron projection bundle; presumptive embryonic/larval system; and synaptic neuropil domain. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; bipolar disorder; drug dependence; middle cerebral artery infarction; and nicotine dependence. Orthologous to human NCAM1 (neural cell adhesion molecule 1) and NCAM2 (neural cell adhesion molecule 2). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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