U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG44774 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31424, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
CG44774provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0266000
Locus tag
Dmel_CG44774
See related
AllianceGenome:FB:FBgn0266000
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG4068; CR43698; CR43699; Dmel\CG44774; hp-CG4068
Old locus tag
Dmel_CG4068; Dmel_CR43698; Dmel_CR43699
Summary
Predicted to be involved in negative regulation of cell migration. Predicted to be part of Sin3-type complex. Is expressed in several structures, including auditory system neurons; embryonic/larval midgut primordium; ganglia; gut section; and mesoderm. Orthologous to human SINHCAF (SIN3-HDAC complex associated factor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG44774 in Genome Data Viewer
Location:
4D6-4D7; 1-9 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (4926664..4938105, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (4815711..4832138, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene hairpin RNA:CR46342 Neighboring gene uncharacterized protein Neighboring gene Heparan-alpha-glucosaminide N-acetyltransferase Neighboring gene long non-coding RNA:CR44833 Neighboring gene Protein tyrosine phosphatase 4E Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Organization of projection neurons and local neurons of the primary auditory center in the fruit fly Drosophila melanogaster. Matsuo E, et al. J Comp Neurol, 2016 Apr 15. PMID 26762251
  2. Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila. Marques JT, et al. Nat Struct Mol Biol, 2010 Jan. PMID 20037596, Free PMC Article
  3. Redundancy and compensation in axon guidance: genetic analysis of the Drosophila Ptp10D/Ptp4E receptor tyrosine phosphatase subfamily. Jeon M, et al. Neural Dev, 2008 Jan 31. PMID 18237413, Free PMC Article
  4. Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences. Hartig JV, et al. EMBO J, 2009 Oct 7. PMID 19644447, Free PMC Article
  5. Opposite effects of Drosophila C3PO on gene silencing mediated by esi-2.1 and miRNA-bantam. Liu Y, et al. Acta Biochim Biophys Sin (Shanghai), 2019 Feb 1. PMID 30576408

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in negative regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of cell migration ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
part_of Sin3-type complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Sin3-type complex ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG44774-PA
CG44774-PB
CG44774-PC
CG44774-PD
CG44774-PE
CG44774-PF
CG44774-PG
CG44774-PI

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    4926664..4938105 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001103410.3 → NP_001096880.1  uncharacterized protein Dmel_CG44774, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001096880.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8JUX7, Q8T0A8
    Conserved Domains (1) summary
    pfam15396
    Location:2 → 269
    FAM60A; Protein Family FAM60A

  2. NM_206627.3 → NP_996350.1  uncharacterized protein Dmel_CG44774, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_996350.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0A8, Q9W4F6
    Conserved Domains (1) summary
    pfam15396
    Location:2 → 269
    FAM60A; Protein Family FAM60A

  3. NM_001272319.1 → NP_001259248.1  uncharacterized protein Dmel_CG44774, isoform G [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259248.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0A8, Q9W4F6
    Conserved Domains (1) summary
    pfam15396
    Location:2 → 269
    FAM60A; Protein Family FAM60A

  4. NM_001103411.3 → NP_001096881.1  uncharacterized protein Dmel_CG44774, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001096881.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8JUX7, Q8T0A8
    Conserved Domains (1) summary
    pfam15396
    Location:2 → 269
    FAM60A; Protein Family FAM60A

  5. NM_001103412.2 → NP_001096882.1  uncharacterized protein Dmel_CG44774, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001096882.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A8JUX7, Q8T0A8
    Conserved Domains (1) summary
    pfam15396
    Location:2 → 269
    FAM60A; Protein Family FAM60A

  6. NM_131971.4 → NP_572199.2  uncharacterized protein Dmel_CG44774, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572199.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0A8, Q9W4F6
    Related
    FBpp0309834
    Conserved Domains (1) summary
    pfam15396
    Location:2 → 269
    FAM60A; Protein Family FAM60A

  7. NM_001272318.2 → NP_001259247.1  uncharacterized protein Dmel_CG44774, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259247.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0A8, Q9W4F6
    Conserved Domains (1) summary
    pfam15396
    Location:2 → 269
    FAM60A; Protein Family FAM60A

  8. NM_001297945.1 → NP_001284874.1  uncharacterized protein Dmel_CG44774, isoform I [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001284874.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T0A8, Q9W4F6
    Conserved Domains (1) summary
    pfam15396
    Location:2 → 269
    FAM60A; Protein Family FAM60A
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A8JUX7 A8JUX7
Q8T0A8 Q8T0A8
Q9W4F6 Q9W4F6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools