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Wdr25 WD repeat domain 25 [ Rattus norvegicus (Norway rat) ]

Gene ID: 314443, updated on 4-Jan-2025

Summary

Official Symbol
Wdr25provided by RGD
Official Full Name
WD repeat domain 25provided by RGD
Primary source
RGD:1562505
See related
EnsemblRapid:ENSRNOG00000004733 AllianceGenome:RGD:1562505
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Wdr25l; RGD1562505; RGD1565864
Summary
Orthologous to human WDR25 (WD repeat domain 25). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 40.5), Spleen (RPKM 27.5) and 9 other tissues See more
Orthologs
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Genomic context

See Wdr25 in Genome Data Viewer
Location:
6q32
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (133571790..133704154)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (127807347..127939795)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (132802327..132932254)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25, member 47 Neighboring gene tryptophanyl-tRNA synthetase 1 Neighboring gene brain-enriched guanylate kinase-associated Neighboring gene ribosomal protein S18, pseudogene 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General protein information

Preferred Names
WD repeat-containing protein 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135894.1NP_001129366.1  WD repeat-containing protein 25

    See identical proteins and their annotated locations for NP_001129366.1

    Status: PROVISIONAL

    Source sequence(s)
    BC166712
    UniProtKB/TrEMBL
    B2RYB0, F1LQP6
    Conserved Domains (2) summary
    cd00200
    Location:228532
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:240279
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    133571790..133704154
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063262013.1XP_063118083.1  WD repeat-containing protein 25 isoform X3

  2. XM_006240545.5XP_006240607.1  WD repeat-containing protein 25 isoform X1

    See identical proteins and their annotated locations for XP_006240607.1

    UniProtKB/TrEMBL
    B2RYB0, F1LQP6
    Related
    ENSRNOP00000006281.6, ENSRNOT00000006281.8
    Conserved Domains (2) summary
    cd00200
    Location:228532
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:240279
    7WD40; WD40 repeat [structural motif]
  3. XM_039112407.2XP_038968335.1  WD repeat-containing protein 25 isoform X1

    UniProtKB/TrEMBL
    B2RYB0, F1LQP6
    Conserved Domains (2) summary
    cd00200
    Location:228532
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:240279
    7WD40; WD40 repeat [structural motif]
  4. XM_006240546.5XP_006240608.1  WD repeat-containing protein 25 isoform X1

    See identical proteins and their annotated locations for XP_006240608.1

    UniProtKB/TrEMBL
    B2RYB0, F1LQP6
    Conserved Domains (2) summary
    cd00200
    Location:228532
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:240279
    7WD40; WD40 repeat [structural motif]
  5. XM_063262012.1XP_063118082.1  WD repeat-containing protein 25 isoform X2

  6. XM_039112408.1XP_038968336.1  WD repeat-containing protein 25 isoform X1

    UniProtKB/TrEMBL
    B2RYB0, F1LQP6
    Conserved Domains (2) summary
    cd00200
    Location:228532
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:240279
    7WD40; WD40 repeat [structural motif]