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CG4020 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31522, updated on 9-Dec-2024

Summary

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Official Symbol
CG4020provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0029821
Locus tag
Dmel_CG4020
See related
AllianceGenome:FB:FBgn0029821
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG4020
Summary
Predicted to enable alcohol-forming very long-chain fatty acyl-CoA reductase activity. Predicted to be involved in long-chain fatty-acyl-CoA metabolic process. Predicted to be active in peroxisome. Is expressed in adult head and adult heart. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG4020 in Genome Data Viewer
Location:
5C7-5C7; 1-14 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5905746..5908001)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5799779..5802034)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45668 Neighboring gene uncharacterized protein Neighboring gene Actin 5C Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44108 Neighboring gene Serine hydroxymethyl transferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Birth-and-Death Evolution of the Fatty Acyl-CoA Reductase (FAR) Gene Family and Diversification of Cuticular Hydrocarbon Synthesis in Drosophila. Finet C, et al. Genome Biol Evol, 2019 Jun 1. PMID 31076758, Free PMC Article
  2. Tyrosyl-tRNA synthetase has a noncanonical function in actin bundling. Ermanoska B, et al. Nat Commun, 2023 Mar 8. PMID 36890170, Free PMC Article
  3. Cadmium-induced genome-wide DNA methylation changes in growth and oxidative metabolism in Drosophila melanogaster. Guan DL, et al. BMC Genomics, 2019 May 9. PMID 31072326, Free PMC Article
  4. A fatty acid anabolic pathway in specialized-cells sustains a remote signal that controls egg activation in Drosophila. Poidevin M, et al. PLoS Genet, 2024 Mar. PMID 38483976, Free PMC Article
  5. An inventory of peroxisomal proteins and pathways in Drosophila melanogaster. Faust JE, et al. Traffic, 2012 Oct. PMID 22758915, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables alcohol-forming long-chain fatty acyl-CoA reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables alcohol-forming very long-chain fatty acyl-CoA reductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in long-chain fatty-acyl-CoA metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG4020-PA
CG4020-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    5905746..5908001
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272335.1 → NP_001259264.1  uncharacterized protein Dmel_CG4020, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259264.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q29QU3, Q9W459
    Conserved Domains (2) summary
    cd09071
    Location:359 → 450
    FAR_C; C-terminal domain of fatty acyl CoA reductases
    cd05236
    Location:12 → 333
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs

  2. NM_132048.3 → NP_572276.1  uncharacterized protein Dmel_CG4020, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572276.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q29QU3, Q9W459
    Related
    FBpp0070789
    Conserved Domains (2) summary
    cd09071
    Location:359 → 450
    FAR_C; C-terminal domain of fatty acyl CoA reductases
    cd05236
    Location:12 → 333
    FAR-N_SDR_e; fatty acyl CoA reductases (FARs), extended (e) SDRs
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W459 Q9W459

Gene LinkOut

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