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Fam118b family with sequence similarity 118, member B [ Rattus norvegicus (Norway rat) ]

Gene ID: 315549, updated on 4-Jan-2025

Summary

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Official Symbol
Fam118bprovided by RGD
Official Full Name
family with sequence similarity 118, member Bprovided by RGD
Primary source
RGD:1307173
See related
EnsemblRapid:ENSRNOG00000011543 AllianceGenome:RGD:1307173
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ppp4r1l; RGD1307173
Summary
Predicted to enable identical protein binding activity. Predicted to be located in Cajal body. Orthologous to human FAM118B (family with sequence similarity 118 member B). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Thymus (RPKM 118.6), Spleen (RPKM 92.0) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fam118b in Genome Data Viewer
Location:
8q21
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (41824522..41875190, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (33566681..33617310, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (36416769..36467609, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene FAD-dependent oxidoreductase domain containing 1 Neighboring gene TIR domain containing adaptor protein Neighboring gene SRP receptor subunit alpha Neighboring gene RNA pseudouridine synthase D4 Neighboring gene cell adhesion associated, oncogene regulated like 1 Neighboring gene cell adhesion associated, oncogene regulated

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC116168

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Cajal body IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein FAM118B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001025283.2 → NP_001020454.1  protein FAM118B

    See identical proteins and their annotated locations for NP_001020454.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/Swiss-Prot
    Q4QQT2
    UniProtKB/TrEMBL
    A6JYK2
    Related
    ENSRNOP00000015366.6, ENSRNOT00000015366.9
    Conserved Domains (1) summary
    pfam13289
    Location:158 → 301
    SIR2_2; SIR2-like domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    41824522..41875190 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242784.5 → XP_006242846.1  protein FAM118B isoform X1

    See identical proteins and their annotated locations for XP_006242846.1

    UniProtKB/Swiss-Prot
    Q4QQT2
    UniProtKB/TrEMBL
    A6JYK2
    Conserved Domains (1) summary
    pfam13289
    Location:158 → 301
    SIR2_2; SIR2-like domain

  2. XM_039081400.2 → XP_038937328.1  protein FAM118B isoform X1

    UniProtKB/Swiss-Prot
    Q4QQT2
    UniProtKB/TrEMBL
    A6JYK2
    Conserved Domains (1) summary
    pfam13289
    Location:158 → 301
    SIR2_2; SIR2-like domain

  3. XM_039081401.2 → XP_038937329.1  protein FAM118B isoform X2

    Conserved Domains (1) summary
    pfam13289
    Location:21 → 164
    SIR2_2; SIR2-like domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4QQT2.1 GenPept UniProtKB/Swiss-Prot:Q4QQT2

Gene LinkOut

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