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CG3226 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31597, updated on 9-Dec-2024

Summary

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Official Symbol
CG3226provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0029882
Locus tag
Dmel_CG3226
See related
AllianceGenome:FB:FBgn0029882
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG3226; Q9W3Y3
Summary
Predicted to enable S100 protein binding activity; tubulin binding activity; and ubiquitin protein ligase binding activity. Involved in heart development. Predicted to be active in nucleus. Is expressed in adult head. Orthologous to human CACYBP (calcyclin binding protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG3226 in Genome Data Viewer
Location:
6C3-6C3; 1-18 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (6653113..6654248, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (6547146..6548281, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pickled eggs Neighboring gene long non-coding RNA:CR44817 Neighboring gene uncharacterized protein Neighboring gene Cdc7 kinase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. p23 and HSP20/alpha-crystallin proteins define a conserved sequence domain present in other eukaryotic protein families. Garcia-Ranea JA, et al. FEBS Lett, 2002 Oct 9. PMID 12372593
  2. Deletion of Siah-interacting protein gene in Drosophila causes cardiomyopathy. Casad ME, et al. Mol Genet Genomics, 2012 Apr. PMID 22398840, Free PMC Article
  3. The cytolinker Pigs is a direct target and a negative regulator of Notch signalling. Pines MK, et al. Development, 2010 Mar. PMID 20150280, Free PMC Article
  4. The Hippo signaling pathway interactome. Kwon Y, et al. Science, 2013 Nov 8. PMID 24114784, Free PMC Article
  5. A microtubule interactome: complexes with roles in cell cycle and mitosis. Hughes JR, et al. PLoS Biol, 2008 Apr 22. PMID 18433294, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables S100 protein binding IEA
Inferred from Electronic Annotation
more info
  
enables tubulin binding IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in heart development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in heart development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG3226-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    6653113..6654248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132104.4 → NP_572332.1  uncharacterized protein Dmel_CG3226 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572332.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W3Y3
    Related
    FBpp0070953
    Conserved Domains (2) summary
    cd06468
    Location:68 → 159
    p23_CacyBP; p23_like domain found in proteins similar to Calcyclin-Binding Protein(CacyBP)/Siah-1-interacting protein (SIP). CacyBP/SIP interacts with S100A6 (calcyclin), with some other members of the S100 family, with tubulin, and with Siah-1 and Skp-1. The latter ...
    pfam09032
    Location:3 → 60
    Siah-Interact_N; Siah interacting protein, N terminal
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W3Y3 Q9W3Y3

Gene LinkOut

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