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Snupn snurportin 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 316108, updated on 4-Jan-2025

Summary

Official Symbol
Snupnprovided by RGD
Official Full Name
snurportin 1provided by RGD
Primary source
RGD:1303191
See related
EnsemblRapid:ENSRNOG00000005426 AllianceGenome:RGD:1303191
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Rnut1
Summary
Predicted to enable RNA cap binding activity. Predicted to be involved in RNA import into nucleus; cytoskeleton organization; and protein tetramerization. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of NLS-dependent protein nuclear import complex. Orthologous to human SNUPN (snurportin 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Adrenal (RPKM 42.2), Lung (RPKM 38.9) and 9 other tissues See more
Orthologs
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Genomic context

See Snupn in Genome Data Viewer
Location:
8q24
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (66242940..66286651)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (57347412..57388345)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (61614798..61654809)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15a like 7 Neighboring gene IMP U3 small nucleolar ribonucleoprotein 3 Neighboring gene uncharacterized LOC103693102 Neighboring gene protein tyrosine phosphatase, non-receptor type 9 Neighboring gene uncharacterized LOC102553607 Neighboring gene uncharacterized LOC120094171 Neighboring gene SIN3 transcription regulator family member A

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC95000

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables RNA cap binding TAS
Traceable Author Statement
more info
PubMed 
enables nuclear import signal receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in RNA import into nucleus ISO
Inferred from Sequence Orthology
more info
 
involved_in RNA import into nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
involved_in cytoskeleton organization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein complex oligomerization ISO
Inferred from Sequence Orthology
more info
 
involved_in protein complex oligomerization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein import into nucleus IEA
Inferred from Electronic Annotation
more info
 
involved_in protein tetramerization ISO
Inferred from Sequence Orthology
more info
 
involved_in protein tetramerization ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in snRNA import into nucleus IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of NLS-dependent protein nuclear import complex ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
part_of nuclear cap binding complex TAS
Traceable Author Statement
more info
PubMed 
part_of nuclear pore TAS
Traceable Author Statement
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
snurportin-1
Names
RNA U transporter 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004270.1NP_001004270.1  snurportin-1

    See identical proteins and their annotated locations for NP_001004270.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079451
    UniProtKB/Swiss-Prot
    Q68FP5
    UniProtKB/TrEMBL
    A6J4S2
    Related
    ENSRNOP00000110228.1, ENSRNOT00000170389.1
    Conserved Domains (2) summary
    cd09232
    Location:98282
    Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
    pfam11538
    Location:2564
    Snurportin1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    66242940..66286651
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063265671.1XP_063121741.1  snurportin-1 isoform X2

  2. XM_063265667.1XP_063121737.1  snurportin-1 isoform X2

  3. XM_063265672.1XP_063121742.1  snurportin-1 isoform X8

  4. XM_039081670.2XP_038937598.1  snurportin-1 isoform X9

    Conserved Domains (2) summary
    cd09232
    Location:98202
    Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
    pfam11538
    Location:2564
    Snurportin1
  5. XM_063265673.1XP_063121743.1  snurportin-1 isoform X10

    UniProtKB/TrEMBL
    A6J4S1
  6. XM_006243124.2XP_006243186.1  snurportin-1 isoform X3

    Related
    ENSRNOP00000103426.1, ENSRNOT00000129195.1
    Conserved Domains (2) summary
    cd09232
    Location:116300
    Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
    pfam11538
    Location:4382
    Snurportin1
  7. XM_039081669.2XP_038937597.1  snurportin-1 isoform X7

    Conserved Domains (2) summary
    cd09232
    Location:116220
    Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
    pfam11538
    Location:4382
    Snurportin1
  8. XM_063265666.1XP_063121736.1  snurportin-1 isoform X1

  9. XM_063265670.1XP_063121740.1  snurportin-1 isoform X2

    Related
    ENSRNOP00000099920.1, ENSRNOT00000132077.1
  10. XM_063265668.1XP_063121738.1  snurportin-1 isoform X2

  11. XM_006243128.5XP_006243190.1  snurportin-1 isoform X4

    Conserved Domains (2) summary
    cd09232
    Location:116274
    Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
    pfam11538
    Location:4382
    Snurportin1; Snurportin1
  12. XM_039081666.2XP_038937594.1  snurportin-1 isoform X5

    Conserved Domains (2) summary
    cd09232
    Location:116274
    Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
    pfam11538
    Location:4382
    Snurportin1
  13. XM_039081668.2XP_038937596.1  snurportin-1 isoform X6

    Conserved Domains (2) summary
    cd09232
    Location:116220
    Snurportin-1_C; C-terminal m3G cap-binding domain of nuclear import adaptor snurportin-1
    pfam11538
    Location:4382
    Snurportin1