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C3G - C3G guanyl-nucleotide exchange factor

Enables guanyl-nucleotide exchange factor activity. Involved in several processes, including Ras protein signal transduction; positive regulation of smoothened signaling pathway; and sarcomere organization. Predicted to be active in plasma membrane. Is expressed in several structures, including adult head; gut section; larval central nervous system; somatic mesoderm; and visceral mesoderm. Orthologous to human RAPGEF1 (Rap guanine nucleotide exchange factor 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa