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Actr1b actin related protein 1B [ Rattus norvegicus (Norway rat) ]

Gene ID: 316333, updated on 27-Nov-2024

Summary

Official Symbol
Actr1bprovided by RGD
Official Full Name
actin related protein 1Bprovided by RGD
Primary source
RGD:1307380
See related
EnsemblRapid:ENSRNOG00000016789 AllianceGenome:RGD:1307380
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be located in centrosome and cytoplasm. Predicted to be part of dynactin complex. Orthologous to human ACTR1B (actin related protein 1B). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 300.1), Heart (RPKM 295.4) and 9 other tissues See more
Orthologs
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Genomic context

See Actr1b in Genome Data Viewer
Location:
9q21
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 9 NC_086027.1 (46424677..46434341, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 9 NC_051344.1 (38928819..38938483, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (43267053..43276717, complement)

Chromosome 9 - NC_086027.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120094668 Neighboring gene cytochrome c oxidase subunit 5B Neighboring gene similar to human chromosome 2 open reading frame 92 Neighboring gene U4 spliceosomal RNA Neighboring gene zeta chain of T cell receptor associated protein kinase 70

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC116310

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of dynactin complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
beta-centractin
Names
ARP1 actin related protein 1 homolog B
ARP1 actin-related protein 1 homolog B, centractin beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039028.2NP_001034117.2  beta-centractin

    See identical proteins and their annotated locations for NP_001034117.2

    Status: VALIDATED

    Source sequence(s)
    BC085338, BQ203129, BQ206830, CO556025, DY315273, EV779654
    UniProtKB/TrEMBL
    B2RYJ7, F7F067
    Related
    ENSRNOP00000093915.2, ENSRNOT00000076692.3
    Conserved Domains (1) summary
    cl17037
    Location:5376
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086027.1 Reference GRCr8

    Range
    46424677..46434341 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)