Nek2 - Nek2
Enables protein serine/threonine kinase activity. Involved in compound eye photoreceptor cell differentiation; positive regulation of canonical Wnt signaling pathway; and regulation of mitotic nuclear division. Located in centrosome and midbody. Is expressed in several structures, including anlage in statu nascendi; antennal anlage; endoderm anlage; head epidermis primordium; and mesoderm. Used to study cancer. Human ortholog(s) of this gene implicated in retinitis pigmentosa 67. Orthologous to human NEK2 (NIMA related kinase 2). [provided by Alliance of Genome Resources, Nov 2024]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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