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dpr14 defective proboscis extension response 14 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31702, updated on 9-Dec-2024

Summary

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Official Symbol
dpr14provided by FlyBase
Official Full Name
defective proboscis extension response 14provided by FlyBase
Primary source
FLYBASE:FBgn0029974
Locus tag
Dmel_CG10946
See related
AllianceGenome:FB:FBgn0029974
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG10946; CT30653; Dmel\CG10946; Dpr-14; Dpr14
Summary
Involved in synapse organization. Predicted to be located in plasma membrane. Predicted to be active in neuron projection membrane. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See dpr14 in Genome Data Viewer
Location:
7C2-7C2; 1-21 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7903704..7908286, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7797737..7802319, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Ribosomal protein S6 Neighboring gene by S6 Neighboring gene spidey Neighboring gene snazarus

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. BEAF regulates cell-cycle genes through the controlled deposition of H3K9 methylation marks into its conserved dual-core binding sites. Emberly E, et al. PLoS Biol, 2008 Dec 23. PMID 19108610, Free PMC Article
  2. Defective proboscis extension response (DPR), a member of the Ig superfamily required for the gustatory response to salt. Nakamura M, et al. J Neurosci, 2002 May 1. PMID 11978823, Free PMC Article
  3. Neural immunoglobulin superfamily interaction networks. Zinn K, et al. Curr Opin Neurobiol, 2017 Aug. PMID 28558267, Free PMC Article
  4. Systematic expression profiling of Dpr and DIP genes reveals cell surface codes in Drosophila larval motor and sensory neurons. Wang Y, et al. Development, 2022 May 15. PMID 35502740, Free PMC Article
  5. Computational Assessment of Protein-Protein Binding Specificity within a Family of Synaptic Surface Receptors. Nandigrami P, et al. J Phys Chem B, 2022 Oct 6. PMID 35787023

See all (38) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in synapse organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in synapse organization IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
is_active_in neuron projection membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
defective proboscis extension response 14
Names
CG10946-PA
CG10946-PB
dpr14-PA
dpr14-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    7903704..7908286 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001258644.2 → NP_001245573.1  defective proboscis extension response 14, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001245573.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q961K3, Q9W3N2
    Conserved Domains (3) summary
    cd00096
    Location:201 → 274
    Ig; Immunoglobulin domain
    smart00410
    Location:191 → 279
    IG_like; Immunoglobulin like
    cl11960
    Location:84 → 169
    Ig; Immunoglobulin domain

  2. NM_132191.3 → NP_572419.1  defective proboscis extension response 14, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572419.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q961K3, Q9W3N2
    Related
    FBpp0071086
    Conserved Domains (3) summary
    cd00096
    Location:201 → 274
    Ig; Immunoglobulin domain
    smart00410
    Location:191 → 279
    IG_like; Immunoglobulin like
    cl11960
    Location:84 → 169
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W3N2 Q9W3N2

Gene LinkOut

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