spidey - spidey

Predicted to enable very-long-chain 3-oxoacyl-CoA reductase activity. Involved in cellular response to nutrient levels; negative regulation of cell growth; and positive regulation of lipid storage. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including embryonic/larval midgut primordium; ganglia; head epidermis primordium; mesoderm; and visceral mesoderm derivative. Human ortholog(s) of this gene implicated in 17-beta hydroxysteroid dehydrogenase 3 deficiency and disorder of sexual development. Orthologous to several human genes including HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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