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Mospd1 motile sperm domain containing 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 317312, updated on 4-Jan-2025

Summary

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Official Symbol
Mospd1provided by RGD
Official Full Name
motile sperm domain containing 1provided by RGD
Primary source
RGD:1359486
See related
EnsemblRapid:ENSRNOG00000066239 AllianceGenome:RGD:1359486
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Orthologous to human MOSPD1 (motile sperm domain containing 1). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Heart (RPKM 223.1), Muscle (RPKM 169.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Mospd1 in Genome Data Viewer
Location:
Xq36
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (138019719..138047475, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (133100200..133127960, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (157745939..157774505)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene PABIR family member 2 Neighboring gene PABIR family member 3 Neighboring gene small nuclear ribonucleoprotein polypeptide E, pseudogene 1 Neighboring gene embryonic testis differentiation homolog C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Mospd1, a new player in mesenchymal versus epidermal cell differentiation. Thaler R, et al. J Cell Physiol, 2011 Oct. PMID 21792907
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
motile sperm domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001014107.2 → NP_001014129.1  motile sperm domain-containing protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001014129.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000021
    UniProtKB/Swiss-Prot
    Q5RJS6
    UniProtKB/TrEMBL
    A0A8L2Q064, A0A8L2R7H2, A6KUJ2
    Related
    ENSRNOP00000003192.5, ENSRNOT00000003192.8
    Conserved Domains (1) summary
    pfam00635
    Location:16 → 113
    Motile_Sperm; MSP (Major sperm protein) domain

  2. NM_001434093.1 → NP_001421022.1  motile sperm domain-containing protein 1 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000021
    UniProtKB/Swiss-Prot
    Q5RJS6
    UniProtKB/TrEMBL
    A0A8L2Q064, A0A8L2R7H2, A6KUJ2

  3. NM_001434094.1 → NP_001421023.1  motile sperm domain-containing protein 1 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000021

  4. NM_001434095.1 → NP_001421024.1  motile sperm domain-containing protein 1 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000021
    UniProtKB/TrEMBL
    A0A8I5Y568, A0A8I6AC24

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    138019719..138047475 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017602055.3 → XP_017457544.1  motile sperm domain-containing protein 1 isoform X4

    Conserved Domains (1) summary
    pfam00635
    Location:16 → 113
    Motile_Sperm; MSP (Major sperm protein) domain

  2. XM_006257634.5 → XP_006257696.1  motile sperm domain-containing protein 1 isoform X3

    Conserved Domains (1) summary
    pfam00635
    Location:16 → 113
    Motile_Sperm; MSP (Major sperm protein) domain

  3. XM_006257633.5 → XP_006257695.1  motile sperm domain-containing protein 1 isoform X2

    Related
    ENSRNOP00000076964.2, ENSRNOT00000102965.2
    Conserved Domains (1) summary
    pfam00635
    Location:16 → 113
    Motile_Sperm; MSP (Major sperm protein) domain

  4. XM_063280036.1 → XP_063136106.1  motile sperm domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8L2R7H2
    Related
    ENSRNOP00000112498.1, ENSRNOT00000161890.1

  5. XM_063280041.1 → XP_063136111.1  motile sperm domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A8I5Y568, A0A8I6AC24

  6. XM_063280040.1 → XP_063136110.1  motile sperm domain-containing protein 1 isoform X3

  7. XM_063280039.1 → XP_063136109.1  motile sperm domain-containing protein 1 isoform X2

    UniProtKB/Swiss-Prot
    Q5RJS6
    UniProtKB/TrEMBL
    A0A8L2Q064, A0A8L2R7H2, A6KUJ2

  8. XM_063280037.1 → XP_063136107.1  motile sperm domain-containing protein 1 isoform X2

    UniProtKB/Swiss-Prot
    Q5RJS6
    UniProtKB/TrEMBL
    A0A8L2Q064, A0A8L2R7H2, A6KUJ2

  9. XM_063280038.1 → XP_063136108.1  motile sperm domain-containing protein 1 isoform X2

    UniProtKB/Swiss-Prot
    Q5RJS6
    UniProtKB/TrEMBL
    A0A8L2Q064, A0A8L2R7H2, A6KUJ2
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RJS6.1 GenPept UniProtKB/Swiss-Prot:Q5RJS6

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