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Ir67c Ionotropic receptor 67c [ Drosophila melanogaster (fruit fly) ]

Gene ID: 317838, updated on 4-Jan-2025

Summary

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Official Symbol
Ir67cprovided by FlyBase
Official Full Name
Ionotropic receptor 67cprovided by FlyBase
Primary source
FLYBASE:FBgn0052058
Locus tag
Dmel_CG32058
See related
AllianceGenome:FB:FBgn0052058
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
67c; CG32058; DmelIR67c; Dmel\CG32058; IR67c
Summary
Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in chemosensory neuron of adult labral sensillum 7; labral sense organ neurons; and larval gustatory receptor neuron of the dorsal pharyngeal sense organ. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Ir67c in Genome Data Viewer
Location:
67E3-67E3; 3-33 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (10432384..10434105, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (10425484..10427205, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 67b Neighboring gene Gemin 3 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unpredictable Effects of the Genetic Background of Transgenic Lines in Physiological Quantitative Traits. Evangelou A, et al. G3 (Bethesda), 2019 Nov 5. PMID 31540975, Free PMC Article
  2. A receptor and neuron that activate a circuit limiting sucrose consumption. Joseph RM, et al. Elife, 2017 Mar 23. PMID 28332980, Free PMC Article
  3. Combinatorial Pharyngeal Taste Coding for Feeding Avoidance in Adult Drosophila. Chen YD, et al. Cell Rep, 2019 Oct 22. PMID 31644916, Free PMC Article
  4. Mitochondrial genomic variation drives differential nuclear gene expression in discrete regions of Drosophila gene and protein interaction networks. Mossman JA, et al. BMC Genomics, 2019 Sep 2. PMID 31477008, Free PMC Article
  5. Calcium Taste Avoidance in Drosophila. Lee Y, et al. Neuron, 2018 Jan 3. PMID 29276056, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated monoatomic ion channel activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
ionotropic receptor 67c
Names
CG32058-PA
Ir67c-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    10432384..10434105 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168407.1 → NP_729609.1  ionotropic receptor 67c [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_729609.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IQE2
    Related
    FBpp0076022, FBtr0076293
    Conserved Domains (1) summary
    pfam00060
    Location:288 → 500
    Lig_chan; Ligand-gated ion channel
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IQE2 Q8IQE2

Gene LinkOut

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