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edin elevated during infection [ Drosophila melanogaster (fruit fly) ]

Gene ID: 317900, updated on 4-Jan-2025

Summary

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Official Symbol
edinprovided by FlyBase
Official Full Name
elevated during infectionprovided by FlyBase
Primary source
FLYBASE:FBgn0052185
Locus tag
Dmel_CG32185
See related
AllianceGenome:FB:FBgn0052185
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG32185; Dmel\CG32185; Edin
Summary
Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and humoral immune response. Located in extracellular space. Is expressed in embryonic/larval hemolymph. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See edin in Genome Data Viewer
Location:
74D1-74D1; 3-45 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17494880..17495300)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17487980..17488400)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene quijote Neighboring gene Organic anion transporting polypeptide 74D Neighboring gene U4-U6 small nuclear riboprotein factor 60K Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Intruding Wolbachia Strain from the Moth Fails to Establish Itself in the Fruit Fly Due to Immune and Exclusion Reactions. Liu XC, et al. Curr Microbiol, 2020 Sep. PMID 32506239
  2. Edin Expression in the Fat Body Is Required in the Defense Against Parasitic Wasps in Drosophila melanogaster. Vanha-Aho LM, et al. PLoS Pathog, 2015 May. PMID 25965263, Free PMC Article
  3. Amendment of Altered Immune Response by Curcumin in Drosophila Model of Huntington's Disease. Dhankhar J, et al. J Huntingtons Dis, 2023. PMID 37781812
  4. Transmission of the wMel Wolbachia strain is modulated by its titre and by immune genes in Drosophila melanogaster (Wolbachia density and transmission). Liu XC, et al. J Invertebr Pathol, 2021 May. PMID 33882275
  5. Transdifferentiation and Proliferation in Two Distinct Hemocyte Lineages in Drosophila melanogaster Larvae after Wasp Infection. Anderl I, et al. PLoS Pathog, 2016 Jul. PMID 27414410, Free PMC Article

See all (51) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in defense response to Gram-negative bacterium IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in defense response to Gram-positive bacterium IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in defense response to Gram-positive bacterium IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in humoral immune response IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
elevated during infection
Names
CG32185-PA
edin-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    17494880..17495300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168735.2 → NP_730278.1  elevated during infection [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_730278.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QQ02, Q8IQR7
    Related
    FBpp0074940
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IQR7 Q8IQR7

Gene LinkOut

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