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Drsl4 Drosomycin-like 4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 317954, updated on 4-Jan-2025

Summary

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Official Symbol
Drsl4provided by FlyBase
Official Full Name
Drosomycin-like 4provided by FlyBase
Primary source
FLYBASE:FBgn0052282
Locus tag
Dmel_CG32282
See related
AllianceGenome:FB:FBgn0052282
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG32282; Dmel\CG32282; dro-4; Dro-4; dro4; Dro4; dros4; Drs-lF
Summary
Involved in defense response to fungus. Predicted to be located in extracellular region. Is expressed in organism. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Drsl4 in Genome Data Viewer
Location:
63D1-63D1; 3-8 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3315620..3315942)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3315620..3315942)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Drosomycin-like 2 Neighboring gene Drosomycin-like 3 Neighboring gene Drosomycin-like 5 Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class C

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gene expression, antiparasitic activity, and functional evolution of the drosomycin family. Tian C, et al. Mol Immunol, 2008 Sep. PMID 18657321
  2. Functional role of charged residues in drosomycin, a Drosophila antifungal peptide. Zhang Z, et al. Dev Comp Immunol, 2010 Sep. PMID 20420852
  3. Functional divergence of six isoforms of antifungal peptide Drosomycin in Drosophila melanogaster. Yang WY, et al. Gene, 2006 Sep 1. PMID 16824706
  4. The genetic basis of variation in sexual aggression: Evolution versus social plasticity. Scott AM, et al. Mol Ecol, 2022 May. PMID 35313034
  5. Adult Drosophila melanogaster evolved for antibacterial defense invest in infection-induced expression of both humoral and cellular immunity genes. Ye YH, et al. BMC Res Notes, 2011 Aug 23. PMID 21859495, Free PMC Article

See all (55) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in defense response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in defense response IEA
Inferred from Electronic Annotation
more info
  
involved_in defense response to fungus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in defense response to fungus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 
located_in extracellular region ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
Drosomycin-like 4
Names
CG32282-PA
Drosomycin-4
Drosomycin-like F
Drsl4-PA
drosmycin-4
drosomycin
drosomycin 4
drosomycin-F

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    3315620..3315942
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_168021.3 → NP_728862.1  Drosomycin-like 4 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_728862.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B7FNM4, Q8IRD6
    Related
    FBpp0072925
    Conserved Domains (1) summary
    pfam00304
    Location:28 → 70
    Gamma-thionin; Gamma-thionin family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8IRD6 Q8IRD6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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