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CG32576 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318095, updated on 9-Dec-2024

Summary

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Official Symbol
CG32576provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0052576
Locus tag
Dmel_CG32576
See related
AllianceGenome:FB:FBgn0052576
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-AE003501.1; BcDNA:RE29988; Dmel\CG32576; NEST:bs01h05
Summary
Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and retrograde transport, endosome to Golgi. Predicted to be active in endoplasmic reticulum and membrane. Orthologous to several human genes including GOLT1B (golgi transport 1B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG32576 in Genome Data Viewer
Location:
14B7-14B8; 1-53 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16285953..16288533, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16179986..16182566, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Proteasome alpha4 subunit Neighboring gene easily shocked Neighboring gene Ubiquinol-cytochrome c reductase 14 kDa subunit Neighboring gene cabeza Neighboring gene Endoplasmic reticulum protein 44 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SMN complex member Gemin3 self-interacts and has a functional relationship with ALS-linked proteins TDP-43, FUS and Sod1. Cacciottolo R, et al. Sci Rep, 2019 Dec 10. PMID 31822699, Free PMC Article
  2. Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS. Xia R, et al. Mol Neurodegener, 2012 Mar 24. PMID 22443542, Free PMC Article
  3. The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span. Wang JW, et al. J Clin Invest, 2011 Oct. PMID 21881207, Free PMC Article
  4. Endogenously imprinted genes in Drosophila melanogaster. McEachern LA, et al. Mol Genet Genomics, 2014 Aug. PMID 24658702
  5. X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. Legube G, et al. Genes Dev, 2006 Apr 1. PMID 16547175, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in retrograde transport, endosome to Golgi IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG32576-PA
CG32576-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    16285953..16288533 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001014746.3 → NP_001014746.1  uncharacterized protein Dmel_CG32576, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001014746.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q59E43, Q8SYX1
    Conserved Domains (1) summary
    cl02130
    Location:4 → 116
    Got1; Got1/Sft2-like family

  2. NM_167492.4 → NP_727945.1  uncharacterized protein Dmel_CG32576, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727945.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IR19, Q8SYX1
    Related
    FBpp0074024
    Conserved Domains (1) summary
    cl02130
    Location:4 → 116
    Got1; Got1/Sft2-like family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q59E43 Q59E43
Q8IR19 Q8IR19
Q8SYX1 Q8SYX1

Gene LinkOut

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