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Wsck wsck [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318600, updated on 9-Dec-2024

Summary

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Official Symbol
Wsckprovided by FlyBase
Official Full Name
wsckprovided by FlyBase
Primary source
FLYBASE:FBgn0046685
Locus tag
Dmel_CG31127
See related
AllianceGenome:FB:FBgn0046685
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:LD25626; BcDNA:SD05152; CG31127; Dmel\CG31127; WSCK
Summary
Predicted to enable ATP binding activity. Predicted to be active in plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Wsck in Genome Data Viewer
Location:
96A13-96A13; 3-85 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (24627066..24630075, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (20452788..20455797, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene molting defective Neighboring gene long non-coding RNA:CR46095 Neighboring gene Syntaxin 18 Neighboring gene atlastin Neighboring gene Metallothionein F Neighboring gene puffyeye

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Loss of spastic paraplegia gene atlastin induces age-dependent death of dopaminergic neurons in Drosophila. Lee Y, et al. Neurobiol Aging, 2008 Jan. PMID 17030474
  2. Drosophila Atlastin regulates the stability of muscle microtubules and is required for synapse development. Lee M, et al. Dev Biol, 2009 Jun 15. PMID 19341724
  3. Segmental duplication, microinversion, and gene loss associated with a complex inversion breakpoint region in Drosophila. Calvete O, et al. Mol Biol Evol, 2012 Jul. PMID 22328714, Free PMC Article
  4. Classification of nonenzymatic homologues of protein kinases. Anamika K, et al. Comp Funct Genomics, 2009. PMID 19809514, Free PMC Article
  5. The ligand Sas and its receptor PTP10D drive tumour-suppressive cell competition. Yamamoto M, et al. Nature, 2017 Feb 9. PMID 28092921

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
NOT enables protein kinase activity IKR
Inferred from Key Residues
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
wsck
Names
CG31127-PA
Wsck-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    24627066..24630075 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170155.2 → NP_733018.1  wsck [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733018.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P83097, Q8I0H1, Q95TS7
    Related
    FBpp0084049
    Conserved Domains (4) summary
    smart00219
    Location:493 → 746
    TyrKc; Tyrosine kinase, catalytic domain
    cd00192
    Location:497 → 750
    PTKc; Catalytic domain of Protein Tyrosine Kinases
    pfam00041
    Location:130 → 222
    fn3; Fibronectin type III domain
    pfam01822
    Location:42 → 115
    WSC; WSC domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P83097.2 P83097

Gene LinkOut

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