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CG31262 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318649, updated on 9-Dec-2024

Summary

Official Symbol
CG31262provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0051262
Locus tag
Dmel_CG31262
See related
AllianceGenome:FB:FBgn0051262
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG31262; dSLC5A14
Summary
Predicted to enable symporter activity. Predicted to be involved in sodium ion transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital hypothyroidism and thyroid dyshormonogenesis 1. Orthologous to human SLC5A12 (solute carrier family 5 member 12); SLC5A5 (solute carrier family 5 member 5); and SLC5A8 (solute carrier family 5 member 8). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See CG31262 in Genome Data Viewer
Location:
89F3-89F3; 3-60 cM
Exon count:
11
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17217116..17223074, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13042838..13048796, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Mucin related 89F Neighboring gene Single-strand-selective monofunctional uracil-DNA glycosylase Neighboring gene beaten path IIb Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in sodium ion transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
uncharacterized protein
Names
CG31262-PB
CG31262-PD
CG31262-PE
CG31262-PF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    17217116..17223074 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_169752.2NP_732222.2  uncharacterized protein Dmel_CG31262, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732222.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B5X0M0, Q8IN99
    Conserved Domains (1) summary
    cd11492
    Location:9522
    SLC5sbd_NIS-SMVT; Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain
  2. NM_001144597.2NP_001138069.2  uncharacterized protein Dmel_CG31262, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001138069.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    B5X0M0, Q8IN99
    Conserved Domains (1) summary
    cd11492
    Location:9522
    SLC5sbd_NIS-SMVT; Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain
  3. NM_001170163.1NP_001163634.1  uncharacterized protein Dmel_CG31262, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163634.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    E1JIN1
    Conserved Domains (1) summary
    cl00456
    Location:9126
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  4. NM_001202311.1NP_001189240.1  uncharacterized protein Dmel_CG31262, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001189240.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4JDA5
    Conserved Domains (1) summary
    cl00456
    Location:981
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain