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Ir31a Ionotropic receptor 31a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 318912, updated on 9-Dec-2024

Summary

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Official Symbol
Ir31aprovided by FlyBase
Official Full Name
Ionotropic receptor 31aprovided by FlyBase
Primary source
FLYBASE:FBgn0051718
Locus tag
Dmel_CG31718
See related
AllianceGenome:FB:FBgn0051718
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
31a; CG31718; DmelIR31a; Dmel\CG31718; IR31a
Summary
Predicted to enable ligand-gated monoatomic ion channel activity. Involved in detection of chemical stimulus involved in sensory perception. Predicted to be located in membrane. Is expressed in adult olfactory receptor neuron Ir31a; antennal coeloconic sensillum ac1; and antennal lobe glomerulus VL2p. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Ir31a in Genome Data Viewer
Location:
31E1-31E1; 2-42 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (10405565..10408197)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (10405565..10408197)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Malate dehydrogenase 1 Neighboring gene CCR4-NOT transcription complex subunit 4 Neighboring gene uncharacterized protein Neighboring gene Like Sm protein 4 Neighboring gene Ribosomal protein S27A Neighboring gene Intronic Protein 259 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Olfactory receptor pseudo-pseudogenes. Prieto-Godino LL, et al. Nature, 2016 Nov 3. PMID 27776356, Free PMC Article
  2. Evaluation of the DREAM Technique for a High-Throughput Deorphanization of Chemosensory Receptors in Drosophila. Koerte S, et al. Front Mol Neurosci, 2018. PMID 30356801, Free PMC Article
  3. An ammonium transporter is a non-canonical olfactory receptor for ammonia. Vulpe A, et al. Curr Biol, 2021 Aug 9. PMID 34111404, Free PMC Article
  4. Targeted molecular profiling of rare olfactory sensory neurons identifies fate, wiring, and functional determinants. Arguello JR, et al. Elife, 2021 Mar 5. PMID 33666172, Free PMC Article
  5. Ionotropic Chemosensory Receptors Mediate the Taste and Smell of Polyamines. Hussain A, et al. PLoS Biol, 2016 May. PMID 27145030, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables ligand-gated monoatomic ion channel activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
ionotropic receptor 31a
Names
CG31718-PC
CG31718-PD
Ir31a-PC
Ir31a-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    10405565..10408197
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_164926.2 → NP_723585.2  ionotropic receptor 31a, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_723585.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IPB8
    Conserved Domains (1) summary
    pfam00060
    Location:401 → 622
    Lig_chan; Ligand-gated ion channel

  2. NM_001273417.1 → NP_001260346.1  ionotropic receptor 31a, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260346.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PCT4
    Conserved Domains (1) summary
    pfam00060
    Location:401 → 624
    Lig_chan; Ligand-gated ion channel
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PCT4 M9PCT4
Q8IPB8 Q8IPB8

Gene LinkOut

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