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RpS28b Ribosomal protein S28b [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31897, updated on 9-Dec-2024

Summary

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Official Symbol
RpS28bprovided by FlyBase
Official Full Name
Ribosomal protein S28bprovided by FlyBase
Primary source
FLYBASE:FBgn0030136
Locus tag
Dmel_CG2998
See related
AllianceGenome:FB:FBgn0030136
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2998; Dmel\CG2998; RpS28; RS28_DROME; S28e
Summary
A structural constituent of ribosome. Predicted to be involved in maturation of SSU-rRNA and ribosomal small subunit assembly. Located in cytosolic ribosome. Is expressed in adult heart. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 15 with mandibulofacial dysostosis. Orthologous to human RPS28 (ribosomal protein S28). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See RpS28b in Genome Data Viewer
Location:
8E7-8E7; 1-28 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (9554623..9555661)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9448656..9449694)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene lethal (1) G0320 Neighboring gene long non-coding RNA:CR42767 Neighboring gene uncharacterized protein Neighboring gene Cubilin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Tissue-specific O-GlcNAcylation profiling identifies substrates in translational machinery in Drosophila mushroom body contributing to olfactory learning. Yu H, et al. Elife, 2024 Apr 15. PMID 38619103, Free PMC Article
  2. Opbp is a new architectural/insulator protein required for ribosomal gene expression. Zolotarev N, et al. Nucleic Acids Res, 2017 Dec 1. PMID 29036346, Free PMC Article
  3. Knockdown of Hsc70-5/mortalin induces loss of synaptic mitochondria in a Drosophila Parkinson's disease model. Zhu JY, et al. PLoS One, 2013. PMID 24386261, Free PMC Article
  4. Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching. Hopes T, et al. Nucleic Acids Res, 2022 Feb 28. PMID 34283226, Free PMC Article
  5. Hundreds of putatively functional small open reading frames in Drosophila. Ladoukakis E, et al. Genome Biol, 2011 Nov 25. PMID 22118156, Free PMC Article

See all (59) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
  
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation IC
Inferred by Curator
more info
 PubMed 
involved_in cytoplasmic translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosolic ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of cytosolic small ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ribosomal protein S28b
Names
CG2998-PA
CG2998-PB
RpS28b-PA
RpS28b-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    9554623..9555661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298130.1 → NP_001285059.1  ribosomal protein S28b, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285059.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9W334
    UniProtKB/TrEMBL
    X2JEM4
    Conserved Domains (1) summary
    cd04457
    Location:8 → 65
    S1_S28E; S28E, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. S28E protein is a component of the 30S ribosomal subunit. S28E is highly conserved among archaea and eukaryotes. S28E may control ...

  2. NM_132340.4 → NP_572568.1  ribosomal protein S28b, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572568.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9W334
    UniProtKB/TrEMBL
    X2JEM4
    Related
    FBpp0071295
    Conserved Domains (1) summary
    cd04457
    Location:8 → 65
    S1_S28E; S28E, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. S28E protein is a component of the 30S ribosomal subunit. S28E is highly conserved among archaea and eukaryotes. S28E may control ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W334.2 Q9W334
X2JEM4 X2JEM4

Gene LinkOut

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