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H3c11 H3 clustered histone 11 [ Mus musculus (house mouse) ]

Gene ID: 319153, updated on 27-Nov-2024

Summary

Official Symbol
H3c11provided by MGI
Official Full Name
H3 clustered histone 11provided by MGI
Primary source
MGI:MGI:2448350
See related
Ensembl:ENSMUSG00000101972 AllianceGenome:MGI:2448350
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H3-H; H3c1; H3c8; H3c10; Hist1h3i
Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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Genomic context

See H3c11 in Genome Data Viewer
Location:
13 A3.1; 13 7.97 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (21967085..21967567, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (21782915..21783397, complement)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene 11274 Neighboring gene STARR-positive B cell enhancer ABC_E8510 Neighboring gene STARR-positive B cell enhancer ABC_E11533 Neighboring gene STARR-positive B cell enhancer ABC_E1456 Neighboring gene H1.5 linker histone, cluster member Neighboring gene STARR-seq mESC enhancer starr_33864 Neighboring gene H2A clustered histone 22 Neighboring gene H2B clustered histone 22

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Clone Names

  • MGC144390

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
part_of nucleosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
histone H3.1
Names
histone 1, H3i
histone cluster 1, H3i

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178207.2NP_835514.1  histone H3.1

    See identical proteins and their annotated locations for NP_835514.1

    Status: REVIEWED

    Source sequence(s)
    AL589651
    Consensus CDS
    CCDS26296.1
    UniProtKB/Swiss-Prot
    P68433, Q05A97, Q3B7Z8, Q3B7Z9, Q5T009
    UniProtKB/TrEMBL
    A1L0V4
    Related
    ENSMUSP00000139663.2, ENSMUST00000189457.2
    Conserved Domains (1) summary
    PTZ00018
    Location:1136
    PTZ00018; histone H3; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    21967085..21967567 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)