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CG2972 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31943, updated on 2-Nov-2024

Summary

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Official Symbol
CG2972provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030177
Locus tag
Dmel_CG2972
See related
AllianceGenome:FB:FBgn0030177
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG2972; NOB1
Summary
Predicted to enable RNA endonuclease activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be part of preribosome, small subunit precursor. Orthologous to human NOB1 (NIN1 (RPN12) binding protein 1 homolog). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG2972 in Genome Data Viewer
Location:
9B1-9B1; 1-31 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10083154..10085050)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (9977187..9979083)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45602 Neighboring gene ZAP3 Neighboring gene NAD(P)HX epimerase Neighboring gene RhoU Neighboring gene antisense RNA:CR44894 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of Ribosome Biogenesis and Protein Synthesis Controls Germline Stem Cell Differentiation. Sanchez CG, et al. Cell Stem Cell, 2016 Feb 4. PMID 26669894, Free PMC Article
  2. The phospho-docking protein 14-3-3 regulates microtubule-associated proteins in oocytes including the chromosomal passenger Borealin. Repton C, et al. PLoS Genet, 2022 Jun. PMID 35666772, Free PMC Article
  3. Transcriptional response to dietary restriction in Drosophila melanogaster. Ding F, et al. J Insect Physiol, 2014 Oct. PMID 24819200, Free PMC Article
  4. Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways. Lindsey ARI, et al. mBio, 2021 Feb 9. PMID 33563832, Free PMC Article
  5. An Integrative Analysis of the InR/PI3K/Akt Network Identifies the Dynamic Response to Insulin Signaling. Vinayagam A, et al. Cell Rep, 2016 Sep 13. PMID 27626673, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables RNA endonuclease activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA endonuclease activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal small subunit biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of preribosome, small subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG2972-PA
CG2972-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    10083154..10085050
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298143.1 → NP_001285072.1  uncharacterized protein Dmel_CG2972, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285072.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W2Y4
    Conserved Domains (3) summary
    cd09876
    Location:11 → 120
    PIN_Nob1; PIN domain of eukaryotic ribosome assembly factor Nob1 and archaeal UPF0129 protein Ta0041-like homologs
    pfam08772
    Location:319 → 390
    NOB1_Zn_bind; Nin one binding (NOB1) Zn-ribbon like
    cl14812
    Location:279 → 355
    PIN_SF; PIN (PilT N terminus) domain: Superfamily

  2. NM_132375.3 → NP_572603.1  uncharacterized protein Dmel_CG2972, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572603.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W2Y4
    Related
    FBpp0071365
    Conserved Domains (3) summary
    cd09876
    Location:11 → 120
    PIN_Nob1; PIN domain of eukaryotic ribosome assembly factor Nob1 and archaeal UPF0129 protein Ta0041-like homologs
    pfam08772
    Location:319 → 390
    NOB1_Zn_bind; Nin one binding (NOB1) Zn-ribbon like
    cl14812
    Location:279 → 355
    PIN_SF; PIN (PilT N terminus) domain: Superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W2Y4 Q9W2Y4

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