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Ypel Yippee-like [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31949, updated on 9-Dec-2024

Summary

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Official Symbol
Ypelprovided by FlyBase
Official Full Name
Yippee-likeprovided by FlyBase
Primary source
FLYBASE:FBgn0030183
Locus tag
Dmel_CG15309
See related
AllianceGenome:FB:FBgn0030183
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH10478; CG15309; Dmel\CG15309; dYPEL3; Ypel2
Summary
Involved in regulation of synapse organization. Used to study chromosome 16p11.2 deletion syndrome, 593-kb. Orthologous to several human genes including YPEL2 (yippee like 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Ypel in Genome Data Viewer
Location:
9B3-9B4; 1-31 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10205292..10212374, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10099325..10106407, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44894 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR32690 Neighboring gene long non-coding RNA:CR43899 Neighboring gene ATP synthase, delta subunit Neighboring gene antisense RNA:CR45629 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Frameshift mutations of YPEL3 alter the sensory circuit function in Drosophila. Kim JH, et al. Dis Model Mech, 2020 Jun 3. PMID 32461240, Free PMC Article
  2. Dissecting the complexity of CNV pathogenicity: insights from Drosophila and zebrafish models. Yusuff T, et al. Curr Opin Genet Dev, 2021 Jun. PMID 33812298, Free PMC Article
  3. Identification of novel candidate genes leading to sex differentiation in primordial germ cells of Drosophila. Ota R, et al. Gene Expr Patterns, 2023 Jun. PMID 37142099
  4. Pervasive genetic interactions modulate neurodevelopmental defects of the autism-associated 16p11.2 deletion in Drosophila melanogaster. Iyer J, et al. Nat Commun, 2018 Jun 29. PMID 29959322, Free PMC Article
  5. Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight. Cahill T, et al. Int J Mol Sci, 2021 Aug 31. PMID 34502375, Free PMC Article

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in regulation of synapse organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
Yippee-like
Names
CG15309-PA
CG15309-PB
CG15309-PC
CG15309-PD
CG15309-PE
Ypel-PA
Ypel-PB
Ypel-PC
Ypel-PD
Ypel-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    10205292..10212374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272465.1 → NP_001259394.1  Yippee-like, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259394.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8JUP6, Q9W2X7
    UniProtKB/TrEMBL
    K7X7R3
    Conserved Domains (1) summary
    cl13152
    Location:15 → 103
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  2. NM_001272466.1 → NP_001259395.1  Yippee-like, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259395.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8JUP6, Q9W2X7
    UniProtKB/TrEMBL
    K7X7R3
    Conserved Domains (1) summary
    cl13152
    Location:15 → 103
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  3. NM_001272467.1 → NP_001259396.1  Yippee-like, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259396.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8JUP6, Q9W2X7
    UniProtKB/TrEMBL
    K7X7R3
    Conserved Domains (1) summary
    cl13152
    Location:15 → 103
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  4. NM_132381.4 → NP_572609.1  Yippee-like, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572609.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8JUP6, Q9W2X7
    UniProtKB/TrEMBL
    K7X7R3
    Related
    FBpp0071416
    Conserved Domains (1) summary
    cl13152
    Location:15 → 103
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

  5. NM_001103466.3 → NP_001096936.1  Yippee-like, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001096936.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8JUP6, Q9W2X7
    UniProtKB/TrEMBL
    K7X7R3
    Conserved Domains (1) summary
    cl13152
    Location:15 → 103
    RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
K7X7R3 K7X7R3
Q9W2X7.1 Q9W2X7

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