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TLX2 - T cell leukemia homeobox 2

This gene is a member of an orphan homeobox-containing transcription factor family. Studies of the mouse ortholog have shown that the encoded protein is crucial for the development of the enteric nervous system; in humans, loss-of-function may play a role in tumorigenesis of gastrointestinal stromal tumors. [provided by RefSeq, May 2010]

Genes similar to TLX2

NCBI Orthologs

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Species Gene Architecture aa