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l(1)G0289 lethal (1) G0289 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31964, updated on 9-Dec-2024

Summary

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Official Symbol
l(1)G0289provided by FlyBase
Official Full Name
lethal (1) G0289provided by FlyBase
Primary source
FLYBASE:FBgn0028331
Locus tag
Dmel_CG2221
See related
AllianceGenome:FB:FBgn0028331
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2221; Dmel\CG2221; Mgn1457
Summary
Is expressed in several structures, including adult head; embryonic anal pad; embryonic hypopharynx; gut section; and larval muscle system. Orthologous to human PLXDC1 (plexin domain containing 1) and PLXDC2 (plexin domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See l(1)G0289 in Genome Data Viewer
Location:
9B7-9B12; 1-31 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10348680..10366273, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10250862..10260306, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Overlapping but Distinct Sequences Play Roles in the Insulator and Promoter Activities of the Drosophila BEAF-Dependent scs' Insulator. Maharjan M, et al. Genetics, 2020 Aug. PMID 32554599, Free PMC Article
  2. Cis-regulatory variation is typically polyallelic in Drosophila. Gruber JD, et al. Genetics, 2009 Feb. PMID 19064705, Free PMC Article
  3. Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. Magwire MM, et al. PLoS Genet, 2010 Jul 29. PMID 20686706, Free PMC Article
  4. Diversity and dynamics of the Drosophila transcriptome. Brown JB, et al. Nature, 2014 Aug 28. PMID 24670639, Free PMC Article
  5. Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Lécuyer E, et al. Cell, 2007 Oct 5. PMID 17923096

See all (37) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
lethal (1) G0289
Names
CG2221-PA
CG2221-PB
CG2221-PC
CG2221-PD
l(1)G0289-PA
l(1)G0289-PB
l(1)G0289-PC
l(1)G0289-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    10348680..10366273 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001316627.1 → NP_001303556.1  lethal (1) G0289, isoform C [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W2V9
    Conserved Domains (1) summary
    pfam01437
    Location:421 → 477
    PSI; Plexin repeat

  2. NM_132393.3 → NP_572621.1  lethal (1) G0289, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572621.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W2V9
    Related
    FBpp0071404
    Conserved Domains (1) summary
    pfam01437
    Location:421 → 477
    PSI; Plexin repeat

  3. NM_001414066.1 → NP_001401057.1  lethal (1) G0289, isoform D [Drosophila melanogaster]

    Status: REVIEWED

  4. NM_001316626.1 → NP_001303555.1  lethal (1) G0289, isoform B [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9W2V9
    Conserved Domains (1) summary
    pfam01437
    Location:421 → 477
    PSI; Plexin repeat
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9W2V9 Q9W2V9

Gene LinkOut

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