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CG17841 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 31965, updated on 4-Jan-2025

Summary

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Official Symbol
CG17841provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0028480
Locus tag
Dmel_CG17841
See related
AllianceGenome:FB:FBgn0028480
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-EST:Liang-2.12; BcDNA:GH12326; clone 2.12; Dmel\CG17841
Summary
Predicted to be involved in lipid homeostasis. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including adult head; embryonic/larval oenocyte; gastric caecum; and gut section. Used to study chromosome 16p11.2 deletion syndrome, 593-kb. Human ortholog(s) of this gene implicated in cone-rod dystrophy 22. Orthologous to human TLCD3A (TLC domain containing 3A) and TLCD3B (TLC domain containing 3B). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG17841 in Genome Data Viewer
Location:
9B12-9B14; 1-31 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10368052..10384183)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10262085..10277613)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene lethal (1) G0289 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Partner of Sld Five 3 Neighboring gene flapwing Neighboring gene uncharacterized protein Neighboring gene RabX2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dissecting the complexity of CNV pathogenicity: insights from Drosophila and zebrafish models. Yusuff T, et al. Curr Opin Genet Dev, 2021 Jun. PMID 33812298, Free PMC Article
  2. Genetic modifiers of degeneration in the cathepsin D deficient Drosophila model for neuronal ceroid lipofuscinosis. Kuronen M, et al. Neurobiol Dis, 2009 Dec. PMID 19761846
  3. Pervasive genetic interactions modulate neurodevelopmental defects of the autism-associated 16p11.2 deletion in Drosophila melanogaster. Iyer J, et al. Nat Commun, 2018 Jun 29. PMID 29959322, Free PMC Article
  4. Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. Magwire MM, et al. PLoS Genet, 2010 Jul 29. PMID 20686706, Free PMC Article
  5. An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila. Li-Kroeger D, et al. Elife, 2018 Aug 9. PMID 30091705, Free PMC Article

See all (36) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in lipid homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG17841-PA
CG17841-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    10368052..10384183
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132394.4 → NP_572622.1  uncharacterized protein Dmel_CG17841, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572622.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V3S7
    Related
    FBpp0071379
    Conserved Domains (1) summary
    smart00724
    Location:127 → 397
    TLC; TRAM, LAG1 and CLN8 homology domains

  2. NM_001369989.1 → NP_001356938.1  uncharacterized protein Dmel_CG17841, isoform B [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9V3S7
    Conserved Domains (1) summary
    smart00724
    Location:127 → 397
    TLC; TRAM, LAG1 and CLN8 homology domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9V3S7 Q9V3S7

Gene LinkOut

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