Ant2 - Adenine nucleotide translocase 2
Predicted to enable ATP:ADP antiporter activity. Predicted to be involved in negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway. Predicted to be located in mitochondrial inner membrane. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple); mitochondrial DNA depletion syndrome (multiple); and mitochondrial myopathy (multiple). Orthologous to several human genes including SLC25A4 (solute carrier family 25 member 4); SLC25A5 (solute carrier family 25 member 5); and SLC25A6 (solute carrier family 25 member 6). [provided by Alliance of Genome Resources, Nov 2024]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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