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SmydA-4 SET and MYND domain containing, arthropod-specific, member 4 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32034, updated on 9-Dec-2024

Summary

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Official Symbol
SmydA-4provided by FlyBase
Official Full Name
SET and MYND domain containing, arthropod-specific, member 4provided by FlyBase
Primary source
FLYBASE:FBgn0030257
Locus tag
Dmel_CG11160
See related
AllianceGenome:FB:FBgn0030257
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG11160; Dmel\CG11160
Summary
Predicted to enable histone deacetylase binding activity. Predicted to be involved in negative regulation of gene expression. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See SmydA-4 in Genome Data Viewer
Location:
10A3-10A3; 1-33 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11044756..11049540)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10938789..10943573)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Myosin 10A Neighboring gene C901 Neighboring gene vexed Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Fine mapping of dominant X-linked incompatibility alleles in Drosophila hybrids. Matute DR, et al. PLoS Genet, 2014 Apr. PMID 24743238, Free PMC Article
  2. PAPI, a novel TUDOR-domain protein, complexes with AGO3, ME31B and TRAL in the nuage to silence transposition. Liu L, et al. Development, 2011 May. PMID 21447556, Free PMC Article
  3. Evolutionary History of the Smyd Gene Family in Metazoans: A Framework to Identify the Orthologs of Human Smyd Genes in Drosophila and Other Animal Species. Calpena E, et al. PLoS One, 2015. PMID 26230726, Free PMC Article
  4. A Drosophila Smyd4 homologue is a muscle-specific transcriptional modulator involved in development. Thompson EC, et al. PLoS One, 2008 Aug 20. PMID 18714374, Free PMC Article
  5. Comparative genomic analysis of SET domain family reveals the origin, expansion, and putative function of the arthropod-specific SmydA genes as histone modifiers in insects. Jiang F, et al. Gigascience, 2017 Jun 1. PMID 28444351, Free PMC Article

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables histone deacetylase binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein-lysine N-methyltransferase activity NAS
Non-traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of gene expression ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
SET and MYND domain containing, arthropod-specific, member 4
Names
CG11160-PA
CG11160-PB
CG11160-PC
SmydA-4-PA
SmydA-4-PB
SmydA-4-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11044756..11049540
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001272507.2 → NP_001259436.1  SET and MYND domain containing, arthropod-specific, member 4, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001259436.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    M9PHK0

  2. NM_167262.3 → NP_727478.1  SET and MYND domain containing, arthropod-specific, member 4, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_727478.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8IR97, Q8SWU5
    Related
    FBpp0073247

  3. NM_132447.3 → NP_572675.1  SET and MYND domain containing, arthropod-specific, member 4, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572675.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VZ41
    Related
    FBpp0073246
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
M9PHK0 M9PHK0
Q8IR97 Q8IR97
Q8SWU5 Q8SWU5
Q9VZ41 Q9VZ41

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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