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Abca15 ATP-binding cassette, sub-family A member 15 [ Mus musculus (house mouse) ]

Gene ID: 320631, updated on 9-Dec-2024

Summary

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Official Symbol
Abca15provided by MGI
Official Full Name
ATP-binding cassette, sub-family A member 15provided by MGI
Primary source
MGI:MGI:2388709
See related
Ensembl:ENSMUSG00000054746 AllianceGenome:MGI:2388709
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930500I12Rik
Summary
Predicted to enable ATPase-coupled transmembrane transporter activity and lipid transporter activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in testis. Orthologous to human ABCA15P (ATP binding cassette subfamily A member 15, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Restricted expression toward testis adult (RPKM 4.6) See more
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Genomic context

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See Abca15 in Genome Data Viewer
Location:
7 F2; 7 64.72 cM
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (119927709..120006925)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (120328486..120407702)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene crystallin, mu Neighboring gene ATP-binding cassette, sub-family A member 14 Neighboring gene STARR-seq mESC enhancer starr_20044 Neighboring gene STARR-seq mESC enhancer starr_20045 Neighboring gene STARR-seq mESC enhancer starr_20046 Neighboring gene STARR-seq mESC enhancer starr_20047 Neighboring gene ATP-binding cassette, sub-family A member 16 Neighboring gene STARR-seq mESC enhancer starr_20049 Neighboring gene SEC14 and spectrin domains 1 pseudogene Neighboring gene predicted gene, 32916 Neighboring gene general transcription factor II H, polypeptide 1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Three ATP-binding cassette transporter genes, Abca14, Abca15, and Abca16, form a cluster on mouse Chromosome 7F3. Chen ZQ, et al. Mamm Genome, 2004 May. PMID 15170222
  2. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230
  3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ATPase-coupled transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipid transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within hematopoietic progenitor cell differentiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in lipid transport IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ATP-binding cassette, sub-family A member 15
Names
ATP-binding cassette transporter sub-family A member 15
ATP-binding cassette, sub-family A (ABC1), member 15

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177213.3 → NP_796187.2  ATP-binding cassette, sub-family A member 15

    See identical proteins and their annotated locations for NP_796187.2

    Status: PROVISIONAL

    Source sequence(s)
    AY243471
    Consensus CDS
    CCDS40109.1
    UniProtKB/TrEMBL
    E9PWH4, Q6XBG2
    Related
    ENSMUSP00000075621.4, ENSMUST00000076272.5
    Conserved Domains (4) summary
    cd03263
    Location:522 → 743
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
    COG1131
    Location:522 → 831
    CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
    pfam12698
    Location:1009 → 1231
    ABC2_membrane_3; ABC-2 family transporter protein
    cl21474
    Location:267 → 383
    ABC2_membrane; ABC-2 type transporter

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    119927709..120006925
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006507945.4 → XP_006508008.1  ATP-binding cassette, sub-family A member 15 isoform X1

    UniProtKB/TrEMBL
    E9PWH4
    Conserved Domains (1) summary
    TIGR01257
    Location:108 → 1632
    rim_protein; retinal-specific rim ABC transporter
Nucleotide Protein Strain
Heading Accession and Version

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