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mybphb myosin binding protein Hb [ Danio rerio (zebrafish) ]

Gene ID: 321053, updated on 4-Jan-2025

Summary

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Official Symbol
mybphbprovided by ZNC
Official Full Name
myosin binding protein Hbprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9794
See related
Ensembl:ENSDARG00000003081 AllianceGenome:ZFIN:ZDB-GENE-030131-9794
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb36; sb:cb36; hm:zeh1059; zgc:165344
Summary
Predicted to be involved in sarcomere organization. Predicted to be active in M band. Is expressed in musculature system; myotome; pectoral fin musculature; segmental plate; and somite. Orthologous to human MYBPH (myosin binding protein H). [provided by Alliance of Genome Resources, Jan 2025]
Annotation information
Annotation category: partial on reference assembly
Orthologs
all
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Genomic context

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See mybphb in Genome Data Viewer
Location:
chromosome: 6
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (55032487..55107333)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (55022674..55097520)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene neuron navigator 1b Neighboring gene cysteine and glycine-rich protein 1b Neighboring gene uncharacterized LOC103911280 Neighboring gene synaptotagmin-2 Neighboring gene nuclear factor of activated T-cells, cytoplasmic 2 Neighboring gene mannosidase beta like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish. Lai JKH, et al. Development, 2018 May 17. PMID 29773645
  2. Dietary lysine imbalance affects muscle proteome in zebrafish (Danio rerio): a comparative 2D-DIGE study. de Vareilles M, et al. Mar Biotechnol (NY), 2012 Oct. PMID 22580902
  3. A transcriptomics analysis of the Tbx5 paralogues in zebrafish. Boyle Anderson EAT, et al. PLoS One, 2018. PMID 30532148, Free PMC Article
  4. Patterns of alternative splicing in response to cold acclimation in fish. Healy TM, et al. J Exp Biol, 2019 Mar 7. PMID 30692167
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in sarcomere organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in M band IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
myosin binding protein Hb

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100137.1 → NP_001093607.1  myosin binding protein Hb

    See identical proteins and their annotated locations for NP_001093607.1

    Status: PROVISIONAL

    Source sequence(s)
    BC146703
    UniProtKB/TrEMBL
    A0A8M1NDT3, A6H8Q3
    Related
    ENSDARP00000110377.1, ENSDART00000122794.3
    Conserved Domains (4) summary
    cd00096
    Location:447 → 513
    Ig; Immunoglobulin domain
    cd00063
    Location:124 → 205
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:429 → 518
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:238 → 310
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    55032487..55107333
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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