snu13b SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5) [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: snu13bprovided by ZNC
Official Full Name: SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-9670
See related: Ensembl:ENSDARG00000023299 AllianceGenome:ZFIN:ZDB-GENE-030131-9670
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: Ssfa1; cb127; nhp2l1; nhp2l1b; sb:cb127; zgc:56265
Summary: Predicted to enable RNA binding activity. Acts upstream of or within somite development. Predicted to be located in nucleus. Predicted to be part of box C/D methylation guide snoRNP complex; nucleus; and small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including alar plate midbrain region; immature eye; mesoderm; nervous system; and pectoral fin musculature. Orthologous to human SNU13 (small nuclear ribonucleoprotein 13). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 12

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (10443777..10447178)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (10405934..10409335)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Knockdown of endogenous nhp2l1 in zebrafish disrupts skeletal muscle development.
Title: Post-transcriptional regulation of myotube elongation and myogenesis by Hoi Polloi.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info
involved_in maturation of SSU-rRNA	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within ribosome biogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within somite development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
part_of U4/U6 x U5 tri-snRNP complex	IBA Inferred from Biological aspect of Ancestor more info
part_of box C/D methylation guide snoRNP complex	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of precatalytic spliceosome	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
part_of small-subunit processome	IBA Inferred from Biological aspect of Ancestor more info
part_of spliceosomal complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)

Names: NHP2 non-histone chromosome protein 2-like 1; NHP2 non-histone chromosome protein 2-like 1b

NP_955829.1

EC 3.6.5.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199535.2 → NP_955829.1 SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)

Status: VALIDATED

Source sequence(s)

CT615242, EH537272, EH543208

UniProtKB/TrEMBL

A0A8M1PE15, Q7ZV23

Related

ENSDARP00000038446.5, ENSDART00000029133.7

Conserved Domains (1) summary

cd21104
Location:7 → 128

SNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13