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ATP7 - ATP7

Enables copper ion transmembrane transporter activity. Involved in several processes, including adult chitin-containing cuticle pigmentation; copper ion import across plasma membrane; and intracellular copper ion homeostasis. Located in cytoplasm and plasma membrane. Is expressed in several structures, including epithelial tube; ganglia; gonad; gut section; and organism subdivision. Used to study Menkes disease and metal metabolism disorder. Human ortholog(s) of this gene implicated in Menkes disease; Wilson disease; X-linked distal spinal muscular atrophy 3; cutis laxa; and occipital horn syndrome. Orthologous to several human genes including ATP7B (ATPase copper transporting beta). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to ATP7

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Species Gene Architecture aa