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CG2574 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32190, updated on 9-Dec-2024

Summary

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Official Symbol
CG2574provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030386
Locus tag
Dmel_CG2574
See related
AllianceGenome:FB:FBgn0030386
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
bs21b01.y1; Dmel\CG2574; Ube2E2
Summary
Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG2574 in Genome Data Viewer
Location:
11A9-11A9; 1-38 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (12408861..12409825)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (12302894..12303858)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Ionotropic receptor 11a Neighboring gene long non-coding RNA:CR32652 Neighboring gene uncharacterized protein Neighboring gene Protein kinase C delta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Discovery of insect and human dengue virus host factors. Sessions OM, et al. Nature, 2009 Apr 23. PMID 19396146, Free PMC Article
  2. UbcD4, an ortholog of E2-25K/Ube2K, is essential for activation of the immune deficiency pathway in Drosophila. Park ES, et al. Biochem Biophys Res Commun, 2016 Jan 22. PMID 26707646
  3. Functional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteins. Jones D, et al. Genome Biol, 2002. PMID 11806825, Free PMC Article
  4. What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor? Michelle C, et al. J Mol Evol, 2009 Jun. PMID 19452197, Free PMC Article
  5. Gene discovery using computational and microarray analysis of transcription in the Drosophila melanogaster testis. Andrews J, et al. Genome Res, 2000 Dec. PMID 11116097, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein polyubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein ubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG2574-PA
NP_572796.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    12408861..12409825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132568.3 → NP_572796.1  uncharacterized protein Dmel_CG2574 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572796.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B4F4V4, C0MKV0, Q9VYN3
    Related
    FBpp0073477
    Conserved Domains (2) summary
    COG5078
    Location:66 → 208
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    pfam00179
    Location:66 → 203
    UQ_con; Ubiquitin-conjugating enzyme
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VYN3 Q9VYN3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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