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h1-10 H1.10 linker histone [ Danio rerio (zebrafish) ]

Gene ID: 322508, updated on 4-Jan-2025

Summary

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Official Symbol
h1-10provided by ZNC
Official Full Name
H1.10 linker histoneprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-1228
See related
Ensembl:ENSDARG00000054058 AllianceGenome:ZFIN:ZDB-GENE-030131-1228
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
h1fx; cb1061; wu:fb12d01; wu:fb63d02
Summary
Predicted to enable double-stranded DNA binding activity and nucleosomal DNA binding activity. Predicted to be involved in chromosome condensation and negative regulation of DNA recombination. Predicted to act upstream of or within nucleosome assembly. Predicted to be located in chromosome. Predicted to be part of nucleosome. Predicted to be active in nucleus. Is expressed in peripheral olfactory organ and proliferative region. Orthologous to human H1-10 (H1.10 linker histone). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See h1-10 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (40770286..40771597, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (40772750..40774061, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene myosin, heavy chain b Neighboring gene actin related protein 2/3 complex, subunit 4 Neighboring gene si:ch211-157b11.8 Neighboring gene GATA binding protein 2b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nonspecific cytotoxic cell antimicrobial protein (NCAMP-1): a novel alarmin ligand identified in zebrafish. Monette MM, et al. PLoS One, 2015. PMID 25689842, Free PMC Article
  2. Molecular characterization of a novel pattern recognition protein from nonspecific cytotoxic cells: sequence analysis, phylogenetic comparisons and anti-microbial activity of a recombinant homologue. Evans DL, et al. Dev Comp Immunol, 2005. PMID 15998541
  3. Identification of phagocytic cells, NK-like cytotoxic cell activity and the production of cellular exudates in the coelomic cavity of adult zebrafish. Moss LD, et al. Dev Comp Immunol, 2009 Oct. PMID 19477195
  4. Beneficial Effect of Vitamin D on Non-Alcoholic Fatty Liver Disease (NAFLD) Progression in the Zebrafish Model. Grinberg L, et al. Nutrients, 2023 Mar 10. PMID 36986092, Free PMC Article
  5. Proteome mapping of adult zebrafish marrow neutrophils reveals partial cross species conservation to human peripheral neutrophils. Singh SK, et al. PLoS One, 2013. PMID 24019943, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables double-stranded DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleosomal DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of chromatin IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chromosome condensation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of DNA recombination IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within nucleosome assembly IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
part_of nucleosome IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
histone H1.10
Names
H1 histone family, member X
NCAMP-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199276.1 → NP_954970.1  histone H1.10

    Status: PROVISIONAL

    Source sequence(s)
    BC047192
    UniProtKB/TrEMBL
    Q802U8
    Related
    ENSDARP00000070677.3, ENSDART00000076200.5
    Conserved Domains (1) summary
    pfam00538
    Location:43 → 109
    Linker_histone; linker histone H1 and H5 family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    40770286..40771597 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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