U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MFS10 Major Facilitator Superfamily Transporter 10 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32263, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
MFS10provided by FlyBase
Official Full Name
Major Facilitator Superfamily Transporter 10provided by FlyBase
Primary source
FLYBASE:FBgn0030452
Locus tag
Dmel_CG4330
See related
AllianceGenome:FB:FBgn0030452
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
AA202479; CG4330; Dmel\CG4330
Summary
Predicted to enable transmembrane transporter activity. Involved in negative regulation of cell population proliferation and phosphate ion transport. Predicted to be active in plasma membrane. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MFS10 in Genome Data Viewer
Location:
11E1-11E1; 1-42 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13129018..13134839)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13023051..13028872)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene small non-coding RNA 204 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster. Rollmann SM, et al. Nat Genet, 2006 Jul. PMID 16783380
  2. A phosphate-sensing organelle regulates phosphate and tissue homeostasis. Xu C, et al. Nature, 2023 May. PMID 37138087, Free PMC Article
  3. Roles of major facilitator superfamily transporters in phosphate response in Drosophila. Bergwitz C, et al. PLoS One, 2012. PMID 22359624, Free PMC Article
  4. Genome-wide examination of the transcriptional response to ecdysteroids 20-hydroxyecdysone and ponasterone A in Drosophila melanogaster. Gonsalves SE, et al. BMC Genomics, 2011 Sep 29. PMID 21958154, Free PMC Article
  5. Discriminant analysis to evaluate clustering of gene expression data. Méndez MA, et al. FEBS Lett, 2002 Jul 3. PMID 12095613

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phosphate ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
major facilitator superfamily transporter 10
Names
CG4330-PA
CG4330-PB
CG4330-PC
MFS10-PA
MFS10-PB
MFS10-PC

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    13129018..13134839
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298259.1 → NP_001285188.1  major facilitator superfamily transporter 10, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285188.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YTZ7, Q9VYG7
    Conserved Domains (2) summary
    cd06174
    Location:134 → 538
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:63 → 547
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

  2. NM_001298260.1 → NP_001285189.1  major facilitator superfamily transporter 10, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285189.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YTZ7, Q9VYG7
    Conserved Domains (2) summary
    cd06174
    Location:134 → 538
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:63 → 547
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter

  3. NM_132629.2 → NP_572857.1  major facilitator superfamily transporter 10, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572857.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7YTZ7, Q9VYG7
    Related
    FBpp0073555
    Conserved Domains (2) summary
    cd06174
    Location:134 → 538
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00894
    Location:63 → 547
    2A0114euk; Na(+)-dependent inorganic phosphate cotransporter
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7YTZ7 Q7YTZ7
Q9VYG7 Q9VYG7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous