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HDAC4 - Histone deacetylase 4

Enables histone deacetylase activity. Involved in several processes, including insulin receptor signaling pathway; long-term memory; and positive regulation of DNA-templated transcription. Located in cytosol and nucleus. Is expressed in several structures, including Kenyon cell; adult brain cell body rind; adult mushroom body; calyx of adult mushroom body; and larval ventral nerve cord. Human ortholog(s) of this gene implicated in ataxia telangiectasia; eating disorder; and retinal degeneration. Orthologous to several human genes including HDAC4 (histone deacetylase 4); HDAC5 (histone deacetylase 5); and HDAC9 (histone deacetylase 9). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to HDAC4

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Species Gene Architecture aa