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CG10996 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32345, updated on 9-Dec-2024

Summary

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Official Symbol
CG10996provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030525
Locus tag
Dmel_CG10996
See related
AllianceGenome:FB:FBgn0030525
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10996
Summary
Predicted to enable aldose 1-epimerase activity. Predicted to be involved in galactose catabolic process via UDP-galactose and glucose metabolic process. Predicted to be located in cytosol. Is expressed in spermatozoon. Human ortholog(s) of this gene implicated in galactosemia 4. Orthologous to human GALM (galactose mutarotase). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG10996 in Genome Data Viewer
Location:
12C5-12C5; 1-46 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13796389..13797638, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13690422..13691671, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene amaretto Neighboring gene inactivation no afterpotential E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Chloride intracellular channel

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evidence for the fixation of gene duplications by positive selection in Drosophila. Cardoso-Moreira M, et al. Genome Res, 2016 Jun. PMID 27197209, Free PMC Article
  2. Different modes of APC/C activation control growth and neuron-glia interaction in the developing Drosophila eye. Neuert H, et al. Development, 2017 Dec 15. PMID 29084807
  3. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article
  4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
  5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables aldose 1-epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in galactose catabolic process via UDP-galactose IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glucose metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10996-PA
NP_572924.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    13796389..13797638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_132696.2 → NP_572924.1  uncharacterized protein Dmel_CG10996 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_572924.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q29QR0, Q9VY83
    Related
    FBpp0073667
    Conserved Domains (1) summary
    cd09019
    Location:25 → 363
    galactose_mutarotase_like; galactose mutarotase_like
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VY83 Q9VY83

Gene LinkOut

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