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Fbxl4 - F box and leucine-rich-repeat gene 4

Involved in several processes, including negative regulation of cell communication; negative regulation of circadian sleep/wake cycle, sleep; and protein polyubiquitination. Located in neuron projection and neuronal cell body. Is expressed in eye and retina. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 13. Orthologous to human FBXL4 (F-box and leucine rich repeat protein 4). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa