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HDAC6 - Histone deacetylase 6

Enables histone deacetylase activity. Involved in negative regulation of axon regeneration; neurotransmitter secretion; and regulation of DNA-templated transcription. Located in cytoplasm. Is expressed in adult head and organism. Used to study obesity. Human ortholog(s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Orthologous to human HDAC6 (histone deacetylase 6). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to HDAC6

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Species Gene Architecture aa