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CG6299 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32475, updated on 9-Dec-2024

Summary

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Official Symbol
CG6299provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030641
Locus tag
Dmel_CG6299
See related
AllianceGenome:FB:FBgn0030641
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG6299
Summary
Predicted to enable ceramide 1-phosphate binding activity and ceramide 1-phosphate transfer activity. Predicted to be involved in ceramide transport and intermembrane lipid transfer. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in adult head. Orthologous to human GLTP (glycolipid transfer protein). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See CG6299 in Genome Data Viewer
Location:
13C4-13C4; 1-50 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15462722..15466812)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15356755..15360845)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Adenosylhomocysteinase Neighboring gene uncharacterized protein Neighboring gene shattered Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Grip128 Neighboring gene ALG14, UDP-N-acetylglucosaminyltransferase subunit Neighboring gene maternal haploid

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide phenotypic RNAi screen in the Drosophila wing: global parameters. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599819, Free PMC Article
  2. TFOFinder: Python program for identifying purine-only double-stranded stretches in the predicted secondary structure(s) of RNA targets. Neugroschl A, et al. PLoS Comput Biol, 2023 Aug. PMID 37624852, Free PMC Article
  3. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article
  4. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article
  5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ceramide 1-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ceramide 1-phosphate transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables lipid transfer activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ceramide transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intermembrane lipid transfer IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in intermembrane lipid transfer IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6299-PA
CG6299-PB
CG6299-PC
CG6299-PD
CG6299-PE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15462722..15466812
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176733.4 → NP_788906.1  uncharacterized protein Dmel_CG6299, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788906.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VXV1
    Related
    FBpp0073849
    Conserved Domains (1) summary
    pfam08718
    Location:32 → 163
    GLTP; Glycolipid transfer protein (GLTP)

  2. NM_001298341.1 → NP_001285270.1  uncharacterized protein Dmel_CG6299, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285270.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VXV1
    Conserved Domains (1) summary
    pfam08718
    Location:32 → 163
    GLTP; Glycolipid transfer protein (GLTP)

  3. NM_001298340.1 → NP_001285269.1  uncharacterized protein Dmel_CG6299, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285269.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VXV1
    Conserved Domains (1) summary
    pfam08718
    Location:32 → 163
    GLTP; Glycolipid transfer protein (GLTP)

  4. NM_176732.2 → NP_788905.1  uncharacterized protein Dmel_CG6299, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_788905.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VXV1
    Related
    FBpp0073850
    Conserved Domains (1) summary
    pfam08718
    Location:32 → 163
    GLTP; Glycolipid transfer protein (GLTP)

  5. NM_001298342.1 → NP_001285271.1  uncharacterized protein Dmel_CG6299, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285271.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VXV1
    Conserved Domains (1) summary
    pfam08718
    Location:32 → 163
    GLTP; Glycolipid transfer protein (GLTP)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VXV1 Q9VXV1

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