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CG15602 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 32533, updated on 4-Jan-2025

Summary

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Official Symbol
CG15602provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0030694
Locus tag
Dmel_CG15602
See related
AllianceGenome:FB:FBgn0030694
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG15602
Summary
Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in abscission and mitotic cytokinesis checkpoint signaling. Predicted to be active in centrosome; cleavage furrow; and midbody. Human ortholog(s) of this gene implicated in progressive familial intrahepatic cholestasis. Orthologous to human ZFYVE19 (zinc finger FYVE-type containing 19). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG15602 in Genome Data Viewer
Location:
13F1-13F1; 1-52 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15799426..15800961)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15693459..15694994)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene suppression of retinal degeneration disease 1 upon overexpression 2 Neighboring gene Peptidoglycan recognition protein LE Neighboring gene long non-coding RNA:CR44384 Neighboring gene scalloped

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. MSL2 combines sensor and effector functions in homeostatic control of the Drosophila dosage compensation machinery. Villa R, et al. Mol Cell, 2012 Nov 30. PMID 23084834
  2. Frequent recent origination of brain genes shaped the evolution of foraging behavior in Drosophila. Chen S, et al. Cell Rep, 2012 Feb 23. PMID 22832161, Free PMC Article
  3. In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary. Nguyen TTM, et al. Development, 2023 Feb 15. PMID 36762624
  4. The Drosophila Helicase Maleless (MLE) is Implicated in Functions Distinct From its Role in Dosage Compensation. Cugusi S, et al. Mol Cell Proteomics, 2015 Jun. PMID 25776889, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables phosphatidylinositol-3-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in abscission IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitotic cytokinesis checkpoint signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in cleavage furrow IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in midbody IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG15602-PA
CG15602-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    15799426..15800961
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001298369.1 → NP_001285298.1  uncharacterized protein Dmel_CG15602, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285298.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QQ70, Q9VXP0
    Conserved Domains (1) summary
    cl22851
    Location:2 → 52
    PHD_SF; PHD finger superfamily

  2. NM_132849.3 → NP_573077.2  uncharacterized protein Dmel_CG15602, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_573077.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q4QQ70, Q9VXP0
    Conserved Domains (1) summary
    cl22851
    Location:2 → 52
    PHD_SF; PHD finger superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4QQ70 Q4QQ70

Gene LinkOut

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