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Mfe2 - peroxisomal Multifunctional enzyme type 2

Enables 3-hydroxyacyl-CoA dehydratase activity and protein homodimerization activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be active in peroxisome. Is expressed in adult head and adult heart. Human ortholog(s) of this gene implicated in D-bifunctional protein deficiency; Perrault syndrome; and Stiff-Person syndrome. Orthologous to human HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa