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sl - small wing

Predicted to enable phosphatidylinositol phospholipase C activity. Involved in several processes, including border follicle cell migration; negative regulation of crystal cell differentiation; and negative regulation of signal transduction. Predicted to be active in ruffle membrane. Is expressed in anterior midgut primordium; endoderm; posterior midgut primordium; and spermatozoon. Human ortholog(s) of this gene implicated in familial cold autoinflammatory syndrome 3; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to several human genes including PLCG2 (phospholipase C gamma 2). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa