sst1.1 somatostatin 1, tandem duplicate 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sst1.1provided by ZNC
Official Full Name: somatostatin 1, tandem duplicate 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-4743
See related: Ensembl:ENSDARG00000040799 AllianceGenome:ZFIN:ZDB-GENE-030131-4743
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: SS1; sst1; PPSS1; fd57e04; zgc:92779; wu:fd57e04
Summary: Predicted to enable hormone activity. Predicted to be involved in regulation of cell migration. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in endocrine system; hypoblast; nervous system; and spleen. Orthologous to human SST (somatostatin). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	15	NC_007126.7 (36156986..36158856)
105	previous assembly	GRCz10 (GCF_000002035.5)	15	NC_007126.6 (36299025..36300882)

Chromosome 15 - NC_007126.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Somatostatin signalling coordinates energy metabolism allocation to reproduction in zebrafish.
Title: Somatostatin signalling coordinates energy metabolism allocation to reproduction in zebrafish.
Somatostatin 1.1 contributes to the innate exploration of zebrafish larva.
Title: Somatostatin 1.1 contributes to the innate exploration of zebrafish larva.
identification and expression of two new preprosomatostatins PPSS1 and PPSS3, during zebrafish embryonic development [PPSS1, PPSS3]
Title: Differential expression of two somatostatin genes during zebrafish embryonic development.
The sst1 expression in the temporal lobe of Alzheimer's disease patients is decressed.
Title: Expression of Somatostatin, cortistatin, and their receptors, as well as dopamine receptors, but not of neprilysin, are reduced in the temporal lobe of Alzheimer's disease patients.
we characterized the somatostatin loci in a teleost species, the zebrafish Danio rerio, and compared them with the corresponding regions in the human and pufferfish genomes
Title: Chromosomal localization of three somatostatin genes in zebrafish. Evidence that the [Pro2]-somatostatin-14 isoform and cortistatin are encoded by orthologous genes.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hormone activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of cell migration	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: somatostatin 1, tandem duplicate 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_183070.2 → NP_898893.2 somatostatin 1, tandem duplicate 1 precursor

Status: VALIDATED

Source sequence(s)

BX571880

UniProtKB/TrEMBL

Q8JHX5

Related

ENSDARP00000059790.3, ENSDART00000059791.4