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EbpII Ejaculatory bulb protein II [ Drosophila melanogaster (fruit fly) ]

Gene ID: 326108, updated on 4-Jan-2025

Summary

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Official Symbol
EbpIIprovided by FlyBase
Official Full Name
Ejaculatory bulb protein IIprovided by FlyBase
Primary source
FLYBASE:FBgn0011694
Locus tag
Dmel_CG2665
See related
AllianceGenome:FB:FBgn0011694
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG2665; Dmel\CG2665; FBgn0011694; PEB; PEB2; PebII; PEBII; PEBmeII
Summary
Involved in negative regulation of female receptivity, post-mating. Located in extracellular space. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See EbpII in Genome Data Viewer
Location:
60F5-60F5; 2-107 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (25173568..25174230, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (21061091..21061753, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Seminal fluid protein 60F Neighboring gene Ejaculatory bulb protein Neighboring gene uncharacterized protein Neighboring gene Kruppel

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Discrimination of different species from the genus Drosophila by intact protein profiling using matrix-assisted laser desorption ionization mass spectrometry. Feltens R, et al. BMC Evol Biol, 2010 Apr 7. PMID 20374617, Free PMC Article
  2. Method for attachment of microscopic preparations on glass for in situ hybridization, PRINS and in situ PCR studies. Dyanov HM, et al. Biotechniques, 1995 May. PMID 7619487
  3. A mating plug protein reduces early female remating in Drosophila melanogaster. Bretman A, et al. J Insect Physiol, 2010 Jan. PMID 19800888
  4. The Drosophila melanogaster X-linked mfs(1)6E locus is required for production of normal seminal fluid by the male accessory glands. López PP, et al. Exp Cell Res, 2001 Jul 1. PMID 11412033
  5. Sperm competitive ability in Drosophila melanogaster associated with variation in male reproductive proteins. Fiumera AC, et al. Genetics, 2005 Jan. PMID 15466425, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A polymorphism upstream of PebII may interact with the female genetic background to affect male-induced refractoriness to remating.
    Title: Characterizing male-female interactions using natural genetic variation in Drosophila melanogaster.
  2. PEBII has a subtle but significant role in the prevention of early female remating.
    Title: A mating plug protein reduces early female remating in Drosophila melanogaster.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Process Evidence Code Pubs
involved_in mating plug formation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of female receptivity, post-mating IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sexual reproduction HEP PubMed 
Component Evidence Code Pubs
located_in extracellular region NAS
Non-traceable Author Statement
more info
 PubMed 
located_in extracellular space HDA PubMed 

General protein information

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Preferred Names
ejaculatory bulb protein II
Names
CG2665-PA
CG2665-PB
EbpII-PA
EbpII-PB
protein ejaculatory bulb II

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    25173568..25174230 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299950.1 → NP_001286879.1  ejaculatory bulb protein II, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286879.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q23982, Q4V3M3, Q4V3M4
    UniProtKB/TrEMBL
    A0A0B4LHP4

  2. NM_079142.4 → NP_523866.2  ejaculatory bulb protein II, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523866.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q23982, Q4V3M3, Q4V3M4
    UniProtKB/TrEMBL
    A0A0B4LHP4
    Related
    FBpp0072357
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LHP4 A0A0B4LHP4
Q23982.2 Q23982

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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