hang hangover [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: hangprovided by FlyBase
Official Full Name: hangoverprovided by FlyBase
Primary source: FLYBASE:FBgn0026575
Locus tag: Dmel_CG32575
See related: AllianceGenome:FB:FBgn0026575
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:GM07804; BcDNA:LD22118; CG32575; CG4411; CG4416; Dmel\CG32575; Hang; HANG; LD22118
Summary: Enables mRNA binding activity. Involved in several processes, including behavioral response to ethanol; negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway; and response to heat. Located in nucleus. Is expressed in several structures, including brain; epithelium; follicle cell; germline cell; and head epidermis primordium. Used to study alcohol use disorder. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (16422831..16438454)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (16316864..16332487)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	NAS Non-traceable Author Statement more info	PubMed
enables sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of behavioral response to ethanol	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in behavioral response to ethanol	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to ethanol	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to heat	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to oxidative stress	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info

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