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AGBE - 1,4-Alpha-Glucan Branching Enzyme

Predicted to enable 1,4-alpha-glucan branching enzyme activity. Involved in determination of adult lifespan and intracellular iron ion homeostasis. Predicted to be active in cytosol. Is expressed in several structures, including adult head; adult heart; germline cell; larval muscle system; and larval somatic muscle cell. Used to study porphyria. Human ortholog(s) of this gene implicated in glycogen storage disease IV and pulmonary tuberculosis. Orthologous to human GBE1 (1,4-alpha-glucan branching enzyme 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa