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Chchd2 - Coiled-coil-helix-coiled-coil-helix domain containing 2

Involved in cellular response to oxidative stress. Located in cytosol and nucleoplasm. Is expressed in several structures, including adult brain; adult brain cell body rind; adult gnathal ganglion; gut section; and larval somatic muscle cell. Used to study Parkinson's disease; Parkinson's disease 22; frontotemporal dementia and/or amyotrophic lateral sclerosis 2; and spinal muscular atrophy, Jokela type. Human ortholog(s) of this gene implicated in Parkinson's disease 22; frontotemporal dementia and/or amyotrophic lateral sclerosis 2; isolated mitochondrial myopathy; and spinal muscular atrophy, Jokela type. Orthologous to several human genes including CHCHD2 (coiled-coil-helix-coiled-coil-helix domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to Chchd2

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Species Gene Architecture aa